Brain-targeted drug and gene delivery by intranasal administration

An Overview of Intranasal Nanosuspension for Brain Targeted Drug Delivery

Intranasal Drug Delivery to Brain: an Overview

As the people have been suffering from many CNS disorders like Multiple sclerosis, Alzheimer’s disease, Parkinson’s disease many drugs have been developed but they failed in showing the concentration required for action. But nose to brain drug delivery the drug directly enter into the brain. The objective of this review is to provide overview of nose on an physiological, anatomical and, barrier...

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Targeted Gene Delivery: Importance of Administration Routes

Gene therapy is a promising approach to treat intractable and refractory diseases at the genetic level. Basically, in gene therapy, target gene expression is induced by delivering foreign genes. Downregulation of target gene expression or gene silencing can also be performed using miRNA, siRNA or shRNA expression vectors [1]. Gene therapy is useful for both genetic and acquired diseases. For ge...